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Sunday 29 December 2013
Friday 27 December 2013
A Chemical Tripod
Tripod immobilization of ligands is a simple and flexible strategy for creating new heterogeneous catalysts
A Chemical Tripod
Friday 20 December 2013
Saturday 14 December 2013
Baeyer-Villiger oxidation
Baeyer-Villiger oxidation
Also known as: Baeyer-Villiger rearrangement
The Baeyer-Villiger oxidation is an organic reaction used to convert a ketone to an ester using a peroxyacid (such as mCPBA). The reaction of the ketone with the acid results in a tetrahedral intermediate, with an alkyl migration following to release a carboxylic acid. The more electron rich R group migrates to the oxygen in this concerted process, allowing for accurate prediction of the stereochemistry of the product.[1]
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Mechanism
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References:
1. |
Baeyer, A.; Villiger, V. Ber. Dtsch. Chem. Ges. 1899, 32, 3625–3633.
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Tuesday 10 December 2013
Supercritical Carbon Dioxide: A Promoter of Carbon–Halogen Bond Heterolysis
Angewandte Chemie International Edition
Thais Delgado-Abad, Dr. Jaime MartÃnez-Ferrer, Prof. Dr. Ana Caballero, Dr. Andrea Olmos, Prof. Dr. Rossella Mello, Prof. Dr. MarÃa Elena González-Núñez, Prof. Dr. Pedro J. Pérez and Prof. Dr. Gregorio Asensio
Article first published online: 15 OCT 2013 | DOI: 10.1002/anie.201303819
Amazing reaction medium: Supercritical carbon dioxide, with zero dipole moment, lower dielectric constant than pentane, and non-hydrogen-bonding behavior, ionizes carbon–halogen bonds, dissociates the resulting ion pairs, and escapes from capture by the carbocation intermediates at temperatures above 40 °C. These properties allow the observation of carbocation chemistry in the absence of acids.
Friday 29 November 2013
Cheaper Chlorination of Organic Compounds
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Cheaper Chlorination of Organic Compounds
Safer Methods for Carbonylative Coupling
Read more
Safer Methods for Carbonylative Coupling
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