N-(o-Tolyl)acetamide (3b) White solid, 51.5 mg, 71% yield; m.p. 108.4-109.0 °C (Lit.27 108-109 °C); IR (KBr) n / cm-1 3291, 1647, 1587, 1527, 1458, 1369, 1271, 1116, 1039, 933, 854, 756, 698, 651, 607; 1H NMR (500 MHz, CDCl3) d 2.19 (s, 3H, CH3), 2.30 (s, 3H, CH3), 7.10 (t, 1H, J 7.5 Hz, CH), 7.21 (t, 1H, J 8.0 Hz, CH), 7.71 (d, 1H, J 8.0 Hz, CH); 13C NMR (125 MHz, CDCl3) d 17.8, 24.2, 123.7, 125.4, 126.7, 129.7, 130.5, 135.6, 168.6.
Short ReportJ. Braz. Chem. Soc. 2016
Eco-Friendly, Catalyst and Solvent-Free, Synthesis of Acetanilides and N-Benzothiazole-2-yl-acetamides
Silvio Cunha; Lourenço L. B. de Santana
An expeditious and green synthesis of acetamides is described in good yield without external heating, and with simple purification.
This paper is part of the PubliSBQ Special Issue in honor of the late Prof Angelo da Cunha Pinto.
This paper is part of the PubliSBQ Special Issue in honor of the late Prof Angelo da Cunha Pinto.
http://dx.doi.org/10.21577/0103-5053.20160265
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