An Efficient, Asymmetric Organocatalyst-mediated Conjugate Addition of Nitroalkanes to Unsaturated Cyclic and Acyclic Systems

An Efficient, Asymmetric Organocatalyst-mediated Conjugate Addition of Nitroalkanes to Unsaturated Cyclic and Acyclic Systems 
C.E.T. Mitchell, S.E. Brenner, J. Garcia-Fortanet and S.V. Ley, Org. Biomol. Chem. 2006, 4, 2039-2049.
http://pubs.rsc.org/en/content/articlelanding/2006/ob/b601877g/unauth#!divAbstract 

5-Pyrrolidin-2-yltetrazole is a versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones. Using this catalyst, this transformation requires short reaction times, tolerates a broad substrate scope, and possibly proceeds via generation of an iminium species.