Replacing DEAD with recyclable reagents in the Mitsunobu reaction may lead to it being used for larger-scale industrial processes

Replacing a DEAD, Middle-aged Reagent

Replacing DEAD with recyclable reagents in the Mitsunobu reaction may lead to it being used for larger-scale industrial processes
Read more
at chemistryviews by David Bradley
http://www.chemistryviews.org/details/ezine/4634311/Replacing_a_DEAD_Middle-aged_Reagent.html

The Mitsunobu reaction is an organic reaction that converts an alcohol into a variety of functional groups, such as an ester, using triphenylphosphine and an azodicarboxylate such as diethyl azodicarboxylate (DEAD) or diisopropyl azodicarboxylate (DIAD) The alcohol undergoes an inversion of stereochemistry. It was discovered by Oyo Mitsunobu (1934–2003).

07 May 2013