Muscarine, imidazole, oxazole and thiazole alkaloids

Muscarine, imidazole, oxazole and thiazole alkaloids

 

 

 

Nat. Prod. Rep., 2013, Advance Article
DOI: 10.1039/C3NP70006B, Review Article

Zhong Jin
This review summarizes the latest progress on the isolation, identification,
biological activities, and chemical synthesis of these NPs with a literature
 coverage from July 2010 to June 2012.

 link

 http://pubs.rsc.org/en/Content/ArticleLanding/2013/NP/C3NP70006B?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FNP+%28RSC+-+Nat.+Prod.+Rep.+latest+articles%29

 Structurally diverse alkaloids containing five-membered heterocyclic subunits, 
such as imidazole, oxazole, thiazole, as well as their saturated congeners, 
are widely distributed in terrestrial and marine organisms and microorganisms. 
These naturally occurring secondary metabolites often exhibit extensive and 
pharmacologically important biological activities. 
The latest progress involving isolation, biological activities, chemical synthetic studies, 
and biosynthetic pathways of these natural products has been summarized in this review.